Characterization of somatic antigens of adult Toxocara canis by western blotting

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منابع مشابه

Serodiagnosis of Human Toxocariasis Using Adult Antigens of Toxocara canis

Introduction Toxocara canis has a worldwide distribution and is regarded as the main cause of human toxocariasis (1, 2). Infection in humans, particularly children, is frequently caused by accidental ingestion of embryonated Toxocara eggs present in soil, water, food, dirty hands, and vegetables or by ingestion of larvae in under-cooked giblets (3). The disease can be asymptomatic or can lead t...

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Adult Toxocara canis encephalitis.

A 48-year-old patient with Toxocara canis infection developed severe ataxia, rigor and neuropsychological disturbances. An aetiology was proven by an indirect immunofluorescence test. CT and MRI revealed both diffuse and circumscribed white matter lesions. Angiography showed multiple occlusion of branches of the middle cerebral artery. Anthelminthic treatment was beneficial in the initial stage...

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Identification of toxocara canis antigens by Western blot in experimentally infected rabbits.

Toxocariasis is a frequent helminthiasis that can cause visceral and ocular damage in humans specially in children. The identification of specific antigens of Toxocara canis is important in order to develop better diagnostic techniques. Ten rabbits were infected orally with a dose of 5000 Toxocara canis embryonated eggs. Rabbits were bled periodically and an ELISA assay was performed to determi...

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Identification of candidate antigens from adult stages of Toxocara canis for the serodiagnosis of human toxocariasis.

In the present work, we identified adult Toxocara canis antigens through sodium dodecyl sulfate-polyacrylamide gel electrophoresis for potential use in human toxocariasis immunodiagnosis. The sensitivity and specificity of several semi-purified antigens, as well as their cross-reactivity with other parasitic infections, were assessed by IgM and IgG-enzime linked immunosorbent assay. Whilst we f...

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Toxocara canis and Toxocara catis

mopolitan roundworms that infect dogs, especially puppies, and cats. T. canis infection in humans occurs by ingestion of the embryonic eggs, which are shed in the feces of infected dogs. Toxocariasis is manifested in three different syndromes: visceral larva migrans (VLM), ocular larva migrans (OLM), and covert toxocariasis (1, 2). VLM is usually a disease of children 1 to 6 year old, and it ma...

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ژورنال

عنوان ژورنال: Veterinary World

سال: 2013

ISSN: 0972-8988

DOI: 10.5455/vetworld.2013.424-427